Gene Symbol | EPS8L2 |
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Entrez Gene | 64787 |
Alt Symbol | EPS8R2 |
Species | Human |
Gene Type | protein-coding |
Description | EPS8-like 2 |
Other Description | EPS8-like protein 2|EPS8-related protein 2|epidermal growth factor receptor kinase substrate 8-like protein 2|epidermal growth factor receptor pathway substrate 8-related protein 2 |
Swissprots | Q8WYW7 Q9H6S3 Q53GM8 B7ZKL3 Q9H6K9 Q96K06 B3KSX1 |
Accessions | EAX02375 EAX02376 Q9H6S3 AF318331 AAL55838 AK025588 BAB15180 AK025824 BAB15248 AK027765 BAB55354 AK094539 BAG52883 AK122903 AK122984 AK222903 BAD96623 AK225311 AK294041 BAG57393 AY074929 AAL76118 BC002474 BC080636 AAH80636 BC093878 AAH93878 BC101481 AAI01482 BC143242 AAI43243 NM_022772 NP_073609 |
Function | Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. {ECO:0000269|PubMed:14565974}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14565974}. |
Tissue Specificity | Detected in fibroblasts and placenta. {ECO:0000269|PubMed:14565974}. |
Eps8L2 CRISPR/Cas9 KO Plasmid (h) - sc-413037 from Santa Cruz Biotechnology
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Eps8L2 HDR Plasmid (h) - sc-413037-HDR from Santa Cruz Biotechnology
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Eps8L2 Double Nickase Plasmid (h) - sc-413037-NIC from Santa Cruz Biotechnology
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Eps8L2 Double Nickase Plasmid (h2) - sc-413037-NIC-2 from Santa Cruz Biotechnology
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Eps8L2 CRISPR Activation Plasmid (h) - sc-413037-ACT from Santa Cruz Biotechnology
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Eps8L2 CRISPR Activation Plasmid (h2) - sc-413037-ACT-2 from Santa Cruz Biotechnology
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Eps8L2 Lentiviral Activation Particles (h) - sc-413037-LAC from Santa Cruz Biotechnology
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Eps8L2 Lentiviral Activation Particles (h2) - sc-413037-LAC-2 from Santa Cruz Biotechnology
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Eps8L2 siRNA (h) - sc-96954 from Santa Cruz Biotechnology
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Eps8L2 shRNA Plasmid (h) - sc-96954-SH from Santa Cruz Biotechnology
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Eps8L2 shRNA (h) Lentiviral Particles - sc-96954-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7937 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7937 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06253 from Sigma-Aldrich
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EPS8L2 siRNA (Human) - CRJ2092 from Cohesion Biosciences
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EPS8L2 RNAi - H00064787-R02 from Novus Biologicals
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EPS8L2 - MBS8210505 from MyBioSource
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shRNA set against Human EPS8L2 (NM_022772.3) - SHH286697 from Creative biogene
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Human EPS8L2 siRNA - orb272593 from Biorbyt
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EPS8L2 shRNA Plasmid (Human) - CHJ2092 from Cohesion Biosciences
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EPS8L2 miRNA 3'UTR clone - MiUTR3H-14753 from Creative biogene
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