| Gene Symbol | PLB1 |
|---|---|
| Entrez Gene | 100009309 |
| Alt Symbol | PHLPB |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | phospholipase B1 |
| Other Description | PLB/LIP|phospholipase AdRab-B|phospholipase B|phospholipase B/lipase|phospholipase B1, membrane-associated |
| Swissprots | Q05017 |
| Accessions | Q05017 Z12841 CAA78303 NM_001101708 NP_001095178 |
| Function | Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Can convert phosphatidylcholine to fatty acids and glycerophosphocholine. Could be involved in uptake of dietary lipids, possibly including long chain retinyl esters. {ECO:0000269|PubMed:8509424}. |
| Subcellular Location | Apical cell membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Present in the intestinal brush border membranes. |
| Tissue Specificity | Intestine. {ECO:0000269|PubMed:8509424}. |
| Top Pathways | Vitamin digestion and absorption, Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism |