SUV420H2

Gene Symbol	SUV420H2
Entrez Gene	84787
Alt Symbol	KMT5C
Species	Human
Gene Type	protein-coding
Description	suppressor of variegation 4-20 homolog 2 (Drosophila)
Other Description	histone-lysine N-methyltransferase SUV420H2|lysine N-methyltransferase 5C|su(var)4-20 homolog 2|suv4-20h2
Swissprots	Q9BRZ6 Q86Y97 Q8WZ10
Accessions	EAW72364 EAW72365 EAW72366 Q86Y97 AF289582 AAL55766 AK304562 BAH14216 AK308586 AW248704 BC005842 AAH05842 BC019313 AAH19313 BC044889 AAH44889 XM_005259338 XP_005259395 XM_006723442 XP_006723505 XM_011527415 XP_011525717 XM_011527416 XP_011525718 NM_032701 NP_116090
Function	Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Chromosome {ECO:0000250}. Note=Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity). {ECO:0000250}.
Top Pathways	Lysine degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KMT5C/SUV4-20h2 protein fragment - ab80290 from Abcam Category Protein Source E. coli Species Human

SUV420H2 Antibody Blocking Peptide - LS-E1407 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SUV420H2 Antibody Blocking Peptide - LS-E8245 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SUV4-20H2-Antibody-N-term-Blocking-peptide - BP12073a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SUV4-20H2-Antibody-Center-Blocking-Peptide - BP6511c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SUV420H2 His GST tag protein - orb83912 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source E. coli Species Human

Mouse SUV420H2 Protein - abx069207 from Abbexa Category Protein Source E.coli Species Mouse

Suppressor Of Variegation 4-20 Homolog 2 - 20-9540 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Mouse

SUV420H2 fusion protein - ag14731 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant SUV420H2 protein - 31361 from ActiveMotif Category Protein Prices $395.00 Sizes 50 µg Source E. coli Species Human

Recombinant Human SUV420H2, GST-tagged - SUV420H2-474H from Creative Biomart Category Protein Source E.Coli .

Recombinant Human SUV420H2, His & GST tagged - SUV420H2-1174H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human SUV420H2 - SUV420H2-27744TH from Creative Biomart Category Protein Source E. coli

Recombinant Suppressor Of Variegation 4-20 Homolog 2 (SUV420H2) - RPM970Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Human SUV420H2 Protein (His & GST Tag) - 11971-H20E-20 from Sino Biological Category Protein Prices $138.00, $138.00 Sizes 20 µg, 50 µg Source E. coli Species Human

Recombinant Human Histone-lysine N-methyltransferase SUV420H2(SUV420H2) - CSB-YP769808HU CSB-EP769808HU CSB-BP769808HU CSB-MP769808HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human SUV420H2 Protein (His & GST tag) - PKSH030951 from Elabscience Category Protein Source E. coli Species Human

Recombinant Human SUV420H2 Protein, GST-tagged - SUV420H2-212H from Creative Biomart Category Protein Source Insect cell Species Human

SUV420H2 Recombinant Protein Antigen - NBP2-30524PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

SUV420H2 Peptide, Human - M34GP15431H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human SUV420H2 Protein (His & GST Tag) - 11971-H20E from ABclonal Category Protein Prices $138.00, $298.00 Sizes 20 µg, 50 µg Source E. coli Species Human

Histone-lysine N-methyltransferase SUV420H2 (SUV420H2), Recombinant Protein - MBS1282160 from MyBioSource Category Protein Prices $1,245.00, $1,245.00, $1,460.00, $1,460.00, $2,025.00, $2,025.00, $2,490.00, $2,490.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Suppressor Of Variegation 4-20 Homolog 2 (SUV420H2), Recombinant Protein - MBS2009739 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

SUV420H2, Recombinant Protein - MBS2545618 from MyBioSource Category Protein Prices $375.00, $775.00 Sizes 20 µg, 50 µg Source E Coli

Recombinant SUV420H2 protein - 81013 from ActiveMotif Category Protein Prices $395.00 Sizes 20 µg Source E. coli Species Human

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