CCRN4L

Gene Symbol	CCRN4L
Entrez Gene	25819
Alt Symbol	CCR4L, Ccr4c, NOC
Species	Human
Gene Type	protein-coding
Description	CCR4 carbon catabolite repression 4-like (S. cerevisiae)
Other Description	CCR4 protein homolog|CCR4-like (carbon catabolite repression 4, S.cerevisiae)|carbon catabolite repression 4-like protein|circadian deadenylase NOC|nocturnin
Swissprots	Q9HD95 Q9UK39 D3DNY5 Q9HD94 Q9HD93 Q14D51
Accessions	AAG01387 EAX05129 EAX05130 EAX05131 Q9UK39 AF183961 AAD56548 AF199493 AAG01388 AF199494 AAG01389 BC021963 AAH21963 BC023512 AAH23512 BC077723 AAH77723 BC113494 AAI13495 BC113500 AAI13501 HY067201 NM_012118 NP_036250
Function	Circadian deadenylase which plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Degrades poly(A) tails of specific target mRNAs leading to their degradation and suppression of translation. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. Plays an important role in favoring adipogenesis over osteoblastogenesis and acts as a key regulator of the adipogenesis/osteogenesis balance. Promotes adipogenesis by activating PPARG transcriptional activity in a deadenylase- independent manner by facilitating its nuclear translocation. Regulates circadian expression of NOS2 in the liver and negatively regulates the circadian expression of IGF1 in the bone. Critical for proper development of early embryos (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}.
Tissue Specificity	Adipose tissue. Expression is higher in subcutaneous adipose tissue as compared to visceral adipose tissue. {ECO:0000269|PubMed:22331129}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CCRN4L / Nocturnin ELISA Kit (Sandwich ELISA) - LS-F8035 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 0.313-20 ng/ml

Human CCRN4L ELISA Kit - abx150987 from Abbexa Category ELISA Kit Sensitivity 0.119 ng/ml Range 0.313 ng/ml - 20 ng/ml

Carbon Catabolite Repression 4 Like Protein (CCRN4L), Human, ELISA Kit - SEP294Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.116ng/mL Range 0.312-20ng/mL

CCR4 carbon catabolite repression 4-like (S. cerevisiae) , ELISA Kit - MBS9326273 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Carbon Catabolite Repression 4 Like Protein (CCRN4L) - SEP294Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.113ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Carbon Catabolite Repression 4 Like Protein (CCRN4L) - SEP294Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.113ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human CCRN4L ELISA Kit - orb369501 from Biorbyt Category ELISA Kit Prices $595.00, $672.00 Sizes 48 test, 96 test Range Detection Range: 0.313-20ng/mL Detection low threshold: 0.116ng/mL

Human CCRN4L ELISA Kit - abx572734 from Abbexa Category ELISA Kit Sensitivity 0.116 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human CCRN4L ELISA Kit - E006470 from Biobool Category ELISA Kit Sensitivity Typically less than 0.113ng/mL.

Nocturnin (CCRN4L), ELISA Kit - MBS9361423 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9364626 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9345205 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9358690 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9343467 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9367826 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9363375 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9355060 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9364897 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9354092 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9362828 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9360525 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9367676 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nocturnin (CCRN4L), ELISA Kit - MBS9359361 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein (CCRN4L), ELISA Kit - MBS453638 from MyBioSource Category ELISA Kit Prices $445.00, $590.00, $2,620.00, $5,095.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.116ng/mL Range 0.312-20ng/mL

Nocturnin (CCRN4L), ELISA Kit - MBS9369612 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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