| Gene Symbol |
KRTAP11-1
|
| Entrez Gene |
337880
|
| Alt Symbol |
HACL-1, HACL1, KAP11.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 11-1
|
| Other Description |
high sulfur keratin-associated protein 11.1|keratin-associated protein 11-1
|
| Swissprots |
Q8IUC1 A1L4I8
|
| Accessions |
Q8IUC1 AB096963 BAE46378 AJ457065 CAD29721 BC130555 AAI30556 BC130557 AAI30558 NM_175858 NP_787054
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Expressed in the upper matrix and in the entire hair cortex.
|