DGAT2

Gene Symbol	DGAT2
Entrez Gene	84649
Alt Symbol	ARAT, GS1999FULL, HMFN1045
Species	Human
Gene Type	protein-coding
Description	diacylglycerol O-acyltransferase 2
Other Description	acyl-CoA retinol O-fatty-acyltransferase|diacylglycerol O-acyltransferase homolog 2|diacylglycerol O-acyltransferase-like protein 2|diglyceride acyltransferase 2|retinol O-fatty-acyltransferase
Swissprots	Q8NDB7 Q68CL3 Q96PD7 Q68DJ0 Q9BYE5 Q5U810 A6ND76 Q96BS0
Accessions	CBF67543 CBF90902 CBU92416 CBV04422 EAW74984 EAW74985 Q96PD7 AB048286 BAB40641 AB073384 BAD38635 AF384161 AAK84176 AI126704 AK074203 AK091870 AL834287 CAD38961 AY358532 AAQ88896 AY780646 AY780647 AAV35727 BC015234 AAH15234 CR749377 CAH18230 DB462004 HQ448288 ADQ32768 XM_011545304 XP_011543606 NM_001253891 NP_001240820 NM_032564 NP_115953
Function	Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:14521909}; Multi-pass membrane protein {ECO:0000269|PubMed:14521909}. Lipid droplet {ECO:0000250}.
Tissue Specificity	Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin. {ECO:0000269|PubMed:11481335, ECO:0000269|PubMed:14521909}.
Top Pathways	Fat digestion and absorption, Glycerolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DGAT2 full length protein - ab112427 from Abcam Category Protein Source Wheat germ Species Human

Human DGAT2 protein fragment - ab153553 from Abcam Category Protein Source Wheat germ Species Human

DGAT2 Antibody Blocking Peptide - LS-E26281 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DGAT2 Antibody Blocking Peptide - LS-E10262 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DGAT2 Protein - H00084649-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DGAT2 Protein - H00084649-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DGAT2-Antibody-N-term-Blocking-Peptide - BP9686a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DGAT2 blocking peptide - GTX89134-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Dgat2 Blocking Peptide - 33R-5211 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DGAT2 Blocking Peptide - abx064012 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig

DGAT2 Peptide - AC21-1113-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DGAT2 - H00084649-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DGAT2 - H00084649-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DGAT2 - H00084649-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DGAT2 - H00084649-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DGAT2 Peptide - 45-476P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

DGAT2 fusion protein - ag10719 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DGAT2 fusion protein - ag10748 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human DGAT2, GST-tagged - DGAT2-27397H from Creative Biomart Category Protein Source wheat germ

Recombinant Human DGAT2, GST-tagged - DGAT2-27398H from Creative Biomart Category Protein Source Wheat germ

Recombinant Human DGAT2, GST-tagged - DGAT2-11949H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human DGAT2 - DGAT2-27396TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Diacylglycerol-O-Acyltransferase Homolog 2 (DGAT2) - RPJ272Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

DGAT2 Blocking Peptide - CBP2818 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Pig

DGAT2, Peptide - MBS425051 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

Search more