| Gene Symbol | PLA2G4A |
|---|---|
| Entrez Gene | 100008748 |
| Alt Symbol | CPLA2, PLA2G4 |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| Other Description | Phospholipase A2 group IVA|cytosolic phospholipase A2|phosphatidyl choline 2-acylhydrolase cPLA2 |
| Swissprots | Q9TT38 |
| Accessions | Q9TT38 AF204923 AAF15299 GBCH01157080 XM_008268662 XP_008266884 XM_008268663 XP_008266885 XM_008268664 XP_008266886 NM_001082072 NP_001075541 |
| Function | Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Translocates to membrane vesicles in a calcium-dependent fashion. {ECO:0000250}. |
| Top Pathways | Choline metabolism in cancer, Oxytocin signaling pathway, Inflammatory mediator regulation of TRP channels, Ovarian steroidogenesis, Glutamatergic synapse |