| Gene Symbol | Dao |
|---|---|
| Entrez Gene | 100689280 |
| Alt Symbol | DAAO, DAMOX |
| Species | Hamster |
| Gene Type | protein-coding |
| Description | D-amino-acid oxidase |
| Other Description | D-amino acid oxidase |
| Swissprots | Q9Z302 |
| Accessions | BAA74715 Q9Z302 XM_007609005 XP_007607195 XM_007609006 XP_007607196 XM_007644135 XP_007642325 XM_007644136 XP_007642326 NM_001244409 NP_001231338 |
| Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). {ECO:0000250}. |
| Subcellular Location | Peroxisome {ECO:0000250}. |
| Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |