Gene Symbol | KLRG1 |
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Entrez Gene | 10219 |
Alt Symbol | 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE |
Species | Human |
Gene Type | protein-coding |
Description | killer cell lectin-like receptor subfamily G, member 1 |
Other Description | C-type lectin domain family 15 member A|C-type lectin domain family 15, member A|ITIM-containing receptor MAFA-L|MAFA-like receptor|killer cell lectin-like receptor subfamily G member 1|mast cell function-associated antigen (ITIM-containing) |
Swissprots | O75613 B7ZAM2 O43198 Q96E93 |
Accessions | EAW88594 EAW88595 Q96E93 AF034952 AAC34731 AF081675 AAC32200 AF097358 AAD03719 AI433079 AK301367 BAG62909 AK316337 BAH14708 BC012621 AAH12621 DQ892820 ABM83746 DQ896066 ABM87065 NM_005810 NP_005801 |
Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. {ECO:0000269|PubMed:19604491}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:19604491}; Single-pass type II membrane protein {ECO:0000269|PubMed:19604491}. |
Tissue Specificity | Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells. {ECO:0000269|PubMed:15879103, ECO:0000269|PubMed:9842918}. |
KLRG1 (E-20) - sc-19536 from Santa Cruz Biotechnology
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KLRG1 (H-85) - sc-22828 from Santa Cruz Biotechnology
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KLRG1 (G-20) - sc-23598 from Santa Cruz Biotechnology
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KLRG1 (V-20) - sc-19539 from Santa Cruz Biotechnology
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KLRG1 (N-20) - sc-19535 from Santa Cruz Biotechnology
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Anti-KLRG1 antibody - ab96317 from Abcam
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Anti-KLRG1 antibody - ab172543 from Abcam
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Anti-KLRG1 antibody [EPR11237] - ab170959 from Abcam
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Anti-KLRG1 Antibody - LS-C8377 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (FITC) - LS-C8378 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (Biotin) - LS-C8379 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (Azide-free) - LS-C8381 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (PE) - LS-C8380 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (aa17-28) - LS-C108100 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (clone RFFVII/1) - LS-C191598 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (clone 2F1, FITC) - LS-C188484 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (clone 2F1, Azide-free) - LS-C195678 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (clone RFFVII/1, FITC) - LS-C191599 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (clone 2F1, FITC) - LS-C196514 from LifeSpan Bioscience
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Anti-KLRG1 Antibody - LS-C308684 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (clone 2F1, PE) - LS-C196515 from LifeSpan Bioscience
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Anti-KLRG1 Antibody - LS-C310836 from LifeSpan Bioscience
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Anti-KLRG1 Antibody - LS-C310837 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (HRP) - LS-C318354 from LifeSpan Bioscience
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Anti-KLRG1 Antibody (FITC) - LS-C318358 from LifeSpan Bioscience
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