Gene Symbol | KLRG1 |
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Entrez Gene | 10219 |
Alt Symbol | 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE |
Species | Human |
Gene Type | protein-coding |
Description | killer cell lectin-like receptor subfamily G, member 1 |
Other Description | C-type lectin domain family 15 member A|C-type lectin domain family 15, member A|ITIM-containing receptor MAFA-L|MAFA-like receptor|killer cell lectin-like receptor subfamily G member 1|mast cell function-associated antigen (ITIM-containing) |
Swissprots | O75613 B7ZAM2 O43198 Q96E93 |
Accessions | EAW88594 EAW88595 Q96E93 AF034952 AAC34731 AF081675 AAC32200 AF097358 AAD03719 AI433079 AK301367 BAG62909 AK316337 BAH14708 BC012621 AAH12621 DQ892820 ABM83746 DQ896066 ABM87065 NM_005810 NP_005801 |
Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. {ECO:0000269|PubMed:19604491}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:19604491}; Single-pass type II membrane protein {ECO:0000269|PubMed:19604491}. |
Tissue Specificity | Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells. {ECO:0000269|PubMed:15879103, ECO:0000269|PubMed:9842918}. |
Human KLRG1 protein fragment - ab139253 from Abcam
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KLRG1 Antibody Blocking Peptide - LS-E27060 from LifeSpan Bioscience
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KLRG1 Recombinant Protein - H00010219-P01 from Novus Biologicals
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KLRG1 Partial Recombinant Protein - H00010219-Q01 from Novus Biologicals
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Recombinant Human KLRG1 Protein - NBP2-23172 from Novus Biologicals
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KLRG1 blocking peptide - GTX88416-PEP from GeneTex
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Human KLRG1 protein - orb244910 from Biorbyt
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Human KLRG1 protein - orb191062 from Biorbyt
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KLRG1 protein (His tag) - 30R-2950 from Fitzgerald
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KLRG1 Peptide - AC21-1882-P from Abcore
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KLRG1 (60-189, His-tag) - AR50710PU-N from Acris Antibodies
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KLRG1 (60-189, His-tag) - AR50710PU-S from Acris Antibodies
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KLRG1 - H00010219-P01-10 from Acris Antibodies
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KLRG1 - H00010219-P01-25 from Acris Antibodies
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KLRG1 - H00010219-Q01-10 from Acris Antibodies
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KLRG1 - H00010219-Q01-25 from Acris Antibodies
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KLRG1, 60-189aa, Human, His tag, E.coli - 01-P1886 from ARP American Research Products
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KLRG1 Peptide - 42-156P from ProSci
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KLRG1 fusion protein - ag1407 from Proteintech Group
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Recombinant Human KLRG1, His-tagged - KLRG1-7104H from Creative Biomart
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Recombinant Human KLRG1 - KLRG1-723H from Creative Biomart
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Recombinant Human Killer cell lectin-like receptor subfamily G member 1(KLRG1) - CSB-YP846610HU CSB-BP846610HU CSB-MP846610HU from Cusabio
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Recombinant human Killer cell lectin-like receptor subfamily G member 1 - CSB-EP846610HU from Cusabio
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KLRG1, 60-189aa, Human, His tag, E.coli (Denatured) - ATGP1886 from ATGen
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KLRG1, human recombinant - 7355-50 from Biovision
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