IRF2

Gene Symbol IRF2
Entrez Gene 3660
Alt Symbol IRF-2
Species Human
Gene Type protein-coding
Description interferon regulatory factor 2
Other Description -
Swissprots P14316 Q6IAS7 D6RCK5 H0Y8S3 Q96B99
Accessions CCQ43169 EAX04677 EAX04678 EAX04679 EAX04680 P14316 AA361545 AK312953 BAG35793 BC015803 AAH15803 BP200998 BQ017798 BT007264 AAP35928 BX648934 CR457077 CAG33358 DQ409328 X15949 CAA34073 XM_005262984 XP_005263041 XM_005262986 XP_005263043 XM_011531928 XP_011530230 XM_011531929 XP_011530231 NM_002199 NP_002190
Function Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. {ECO:0000269|PubMed:12738767, ECO:0000269|PubMed:15226432, ECO:0000269|PubMed:18514056, ECO:0000269|PubMed:9540062}.
Subcellular Location Nucleus.
Tissue Specificity Expressed throughout the epithelium of the colon. Also expressed in lamina propria. {ECO:0000269|PubMed:15226432}.

IRF2-Over-expression-Lysate - LY12792a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag IRF2 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the IRF2 gene

IRF2 293T Cell Transient Overexpression Lysate(Denatured) - H00003660-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

IRF2 overexpression lysate - LY400800 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

IRF2 293 Cell Lysate - 400767 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

IRF2 Overexpression Lysate (Denatured) - H00003660-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
IRF2 transfected lysate.

IRF2 Overexpression Lysate (Native) - NBL1-12031 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: IRF2 Overexpression Lysate (Adult Normal) [NBL1-12031] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IRF2.

IRF-2 (h): 293 Lysate - sc-112233 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

IRF2 Over-expression Lysate Product - GWB-F11621 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human IRF2 Knockdown Stable Cell Line - CSC-DC007736 from Creative biogene

Category Cell Line
Species Human
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