IRF2

Gene Symbol	IRF2
Entrez Gene	3660
Alt Symbol	IRF-2
Species	Human
Gene Type	protein-coding
Description	interferon regulatory factor 2
Other Description	-
Swissprots	P14316 Q6IAS7 D6RCK5 H0Y8S3 Q96B99
Accessions	CCQ43169 EAX04677 EAX04678 EAX04679 EAX04680 P14316 AA361545 AK312953 BAG35793 BC015803 AAH15803 BP200998 BQ017798 BT007264 AAP35928 BX648934 CR457077 CAG33358 DQ409328 X15949 CAA34073 XM_005262984 XP_005263041 XM_005262986 XP_005263043 XM_011531928 XP_011530230 XM_011531929 XP_011530231 NM_002199 NP_002190
Function	Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. {ECO:0000269|PubMed:12738767, ECO:0000269|PubMed:15226432, ECO:0000269|PubMed:18514056, ECO:0000269|PubMed:9540062}.
Subcellular Location	Nucleus.
Tissue Specificity	Expressed throughout the epithelium of the colon. Also expressed in lamina propria. {ECO:0000269|PubMed:15226432}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IRF2 full length protein - ab131890 from Abcam Category Protein Source Wheat germ Species Human

Human IRF2 peptide - ab66363 from Abcam Category Peptide

Human IRF2 peptide - ab22943 from Abcam Category Peptide Species Human

Human IRF2 protein fragment - ab59954 from Abcam Category Protein Source E. coli Species Human

IRF2 Antibody Blocking Peptide - LS-E849 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF2 Antibody Blocking Peptide - LS-E10770 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF2 Antibody Blocking Peptide - LS-E10926 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF2 Antibody Blocking Peptide - LS-E25410 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF2 Recombinant Protein - H00003660-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IRF2 Partial Recombinant Protein - H00003660-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human IRF2 Protein - NBC1-18476 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Species Human

IRF2-Antibody-Center-Blocking-peptide - BP11225c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IRF2 blocking peptide - GTX89898-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

IRF 2 Protein (OPPA01513) - OPPA01513 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human IRF 2 protein - orb80394 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

IRF2 protein (His tag) - 80R-1032 from Fitzgerald Category Protein Prices $340.00 Sizes 100 µg Source E.coli

IRF2 Peptide - AC21-0238-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

IRF2 (1-113, His-tag) - AR09056PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 500 µg Source E. coli Species Human

IRF2 (1-113, His-tag) - AR09056PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 100 µg Source E. coli Species Human

IRF2 - H00003660-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

IRF2 - H00003660-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IRF2 - H00003660-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IRF2 - H00003660-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Interferon Regulatory Factor-2, Human Recombinant - 228-10975-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human IRF2 - 228-10975-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

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