IRF2

Gene Symbol IRF2
Entrez Gene 3660
Alt Symbol IRF-2
Species Human
Gene Type protein-coding
Description interferon regulatory factor 2
Other Description -
Swissprots P14316 Q6IAS7 D6RCK5 H0Y8S3 Q96B99
Accessions CCQ43169 EAX04677 EAX04678 EAX04679 EAX04680 P14316 AA361545 AK312953 BAG35793 BC015803 AAH15803 BP200998 BQ017798 BT007264 AAP35928 BX648934 CR457077 CAG33358 DQ409328 X15949 CAA34073 XM_005262984 XP_005263041 XM_005262986 XP_005263043 XM_011531928 XP_011530230 XM_011531929 XP_011530231 NM_002199 NP_002190
Function Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. {ECO:0000269|PubMed:12738767, ECO:0000269|PubMed:15226432, ECO:0000269|PubMed:18514056, ECO:0000269|PubMed:9540062}.
Subcellular Location Nucleus.
Tissue Specificity Expressed throughout the epithelium of the colon. Also expressed in lamina propria. {ECO:0000269|PubMed:15226432}.

IRF-2 CRISPR/Cas9 KO Plasmid (h) - sc-402135 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 HDR Plasmid (h) - sc-402135-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 Double Nickase Plasmid (h) - sc-402135-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 Double Nickase Plasmid (h2) - sc-402135-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 CRISPR Activation Plasmid (h) - sc-402135-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 CRISPR Activation Plasmid (h2) - sc-402135-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 Lentiviral Activation Particles (h) - sc-402135-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 Lentiviral Activation Particles (h2) - sc-402135-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-2 siRNA (h) - sc-35708 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF-2 shRNA Plasmid (h) - sc-35708-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF-2 shRNA (h) Lentiviral Particles - sc-35708-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF2 RNAi - H00003660-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU028731 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10762 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10762 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07562 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07562

IRF2 siRNA (Human) - CRH2453 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IRF2 - MBS827730 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IRF2 (NM_002199.3) - SHH320569 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IRF2(NM_002199.3) - SHL180852 from Creative biogene

Category siRNA
Species Reactivities Human

Human IRF2 siRNA - orb262955 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IRF2 shRNA Plasmid (Human) - CHH2453 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IRF2 miRNA 3'UTR clone - MiUTR1H-04990 from Creative biogene

Species Reactivities Human
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