| Gene Symbol | trim33 |
|---|---|
| Entrez Gene | 733198 |
| Alt Symbol | ecto, ptc7, rfg7, tf1g, tif1g, tif1gamma, tifgamma |
| Species | Xenopus |
| Gene Type | protein-coding |
| Description | tripartite motif containing 33 |
| Other Description | E3 ubiquitin-protein ligase TRIM33|TIF1-gamma|ectodermin|transcription intermediary factor 1-gamma|tripartite motif-containing 33|tripartite motif-containing protein 33 |
| Swissprots | Q56R14 |
| Accessions | Q56R14 AY781409 AAX10105 BC170291 AAI70291 BC170319 AAI70319 NM_001095608 NP_001089077 |
| Function | Acts as an E3 ubiquitin-protein ligase for smad4. Promotes ectoderm embryonic development at the expense of other germ layers. Inhibits mesodermal differentiation. Promotes neural development of the ectoderm. Promotes smad4 alpha degradation via the ubiquitin proteasome pathway. May act as a transcriptional repressor (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:15820681}. |