| Gene Symbol |
CHRNA2
|
| Entrez Gene |
1135
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, alpha 2 (neuronal)
|
| Other Description |
acetylcholine receptor, nicotinic, alpha 2 (neuronal)|cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)|neuronal acetylcholine receptor subunit alpha-2
|
| Swissprots |
J3KMY9 Q9HAQ3 Q15822 B4DK19 A8KAX3
|
| Accessions |
EAW63552 Q15822 AK296348 BAG59031 AK308465 AK314787 AW292180 BC153866 AAI53867 CD013901 DA096824 DA407151 U62431 AAB40109 Y16281 CAA76154 XM_005273397 XP_005273454 XM_006716282 XP_006716345 XM_011544388 XP_011542690 XM_011544389 XP_011542691 NM_000742 NP_000733 NM_001282455 NP_001269384
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: Nicotinic Acetylcholine Receptor alpha 2 Overexpression Lysate (Adult Normal) [NBP2-04175] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Nicotinic Acetylcholine Receptor alpha 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8019_Nicotinic%2520Acetylcholine%2520Receptor%2520alpha%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04175-img0001.jpg)