| Gene Symbol | MAN2A2 |
|---|---|
| Entrez Gene | 4122 |
| Alt Symbol | MANA2X |
| Species | Human |
| Gene Type | protein-coding |
| Description | mannosidase, alpha, class 2A, member 2 |
| Other Description | MAN IIx|alpha-mannosidase 2x|alpha-mannosidase IIx|mannosidase, alpha type II-X|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase|manosidase, alpha-, type II, isozyme X |
| Swissprots | Q13754 A6NH12 A8K1E8 P49641 |
| Accessions | EAX02118 EAX02119 EAX02120 EAX02121 EAX02122 EAX02123 EAX02124 P49641 AF116691 AAF71111 AI361497 AI697595 AK289863 BAF82552 AK293799 BAG57210 AK295646 BAG58516 AK299213 BAG61252 AK308838 AK316150 BAH14521 AL110288 AL832306 BC136448 AAI36449 BC144111 CA442098 D55649 BAA09510 L28821 AAA92022 XM_005254910 XP_005254967 XM_011521562 XP_011519864 XM_011521563 XP_011519865 XM_011521564 XP_011519866 XM_011521565 XP_011519867 XM_011521566 XP_011519868 XR_243208 XR_931828 XR_931829 XR_931830 XR_931831 NM_006122 NP_006113 |
| Function | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Top Pathways | N-Glycan biosynthesis |