| Gene Symbol |
AANAT
|
| Entrez Gene |
15
|
| Alt Symbol |
DSPS, SNAT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
aralkylamine N-acetyltransferase
|
| Other Description |
arylalkylamine N-acetyltransferase|serotonin N-acetyltransferase|serotonin acetylase
|
| Swissprots |
A0AVF2 Q16613 Q562F4 J3KMZ5
|
| Accessions |
AAC50555 AAK49981 BAB20312 BAB20313 BAB20314 BAB20315 BAB20316 EAW89400 Q16613 AA084486 AB593119 BAJ84059 AI819939 AY055827 BC069434 AAH69434 BC092430 AAH92430 BC126332 AAI26333 BC126334 AAI26335 BC143989 HQ448439 ADQ32919 U40347 AAC50554 XM_011524415 XP_011522717 XM_011524416 XP_011522718 XM_011524417 XP_011522719 XM_011524418 XP_011522720 XM_011524419 XP_011522721 XM_011524420 XP_011522722 XM_011524421 XP_011522723 XM_011524422 XP_011522724 XM_011524423 XP_011522725 NM_001088 NP_001079 NM_001166579 NP_001160051 NR_110548
|
| Function |
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11313340}.
|
| Tissue Specificity |
Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. {ECO:0000269|PubMed:18212399, ECO:0000269|PubMed:8661026}.
|
| Top Pathways |
Tryptophan metabolism
|