| Gene Symbol | MKP2 |
|---|---|
| Entrez Gene | 819784 |
| Alt Symbol | ARABIDOPSIS MAPK PHOSPHATASE 2, ATMKP2, DSPTP1B, DUAL-SPECIFICITY PROTEIN PHOSPHATASE 1B, F28L1.5, F28L1_5, MAPK phosphatase 2 |
| Species | Arabidopsis thaliana |
| Gene Type | protein-coding |
| Description | MAPK phosphatase 2 |
| Other Description | - |
| Swissprots | Q8LDW2 Q9M8K7 |
| Accessions | AAF30304 AEE74344 AEE74345 AEE74346 Q9M8K7 AK117443 BAC42108 AY085765 AAM62982 BT005135 AAO50668 NM_001202892 NP_001189821 NM_111486 NP_566272 NM_180191 NP_850522 |
| Function | Has a dual specificity toward Ser/Thr and Tyr-containing proteins. Prevents biotic and abiotic stress responses, including ozone, oxidative stress and pathogen attacks; represses MAPK activities during hypersensitive response to limit the spread of the HR response after infection by necrotrophic pathogen such as Botrytis cinerea. May be also involved in ABA and salt responses. Dephosphorylates MPK3 and MPK6. {ECO:0000269|PubMed:17586809, ECO:0000269|PubMed:20626661, ECO:0000269|PubMed:21057191}. |
| Subcellular Location | Nucleus. Cytoplasm. Note=Upon fungal elicitation, relocalizes surrounding spherical structures that could correspond to epiplasts. |
| Tissue Specificity | Expressed in flowers, seedlings, roots, leaves, and seeds. Present in stomata and meristematic cells. {ECO:0000269|PubMed:20626661}. |