Gene Symbol | KCNIP1 |
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Entrez Gene | 30820 |
Alt Symbol | KCHIP1, VABP |
Species | Human |
Gene Type | protein-coding |
Description | Kv channel interacting protein 1 |
Other Description | A-type potassium channel modulatory protein 1|Kv channel-interacting protein 1|potassium channel interacting protein 1|vesicle APC-binding protein |
Swissprots | Q5U822 Q3YAD1 Q3YAD2 B7Z7B4 Q3YAD3 Q3YAD0 Q9NZI2 |
Accessions | EAW61470 EAW61471 Q9NZI2 AF199597 AAF33682 AI884645 AK074390 AK301775 BAH13550 AY170821 AAN77491 AY780424 AAV51968 BC035032 BC050375 AAH50375 BF514334 DC420716 DQ148476 AAZ77793 DQ148477 AAZ77794 DQ148478 AAZ77795 DQ148479 AAZ77796 XM_006714861 XP_006714924 XM_011534539 XP_011532841 NM_001034837 NP_001030009 NM_001034838 NP_001030010 NM_001278339 NP_001265268 NM_001278340 NP_001265269 NM_014592 NP_055407 |
Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface. {ECO:0000269|PubMed:10676964, ECO:0000269|PubMed:11423117, ECO:0000269|PubMed:12829703, ECO:0000269|PubMed:17187064}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:10676964}; Peripheral membrane protein {ECO:0000305|PubMed:10676964}. Cytoplasm {ECO:0000269|PubMed:10676964}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8R426}. |
Tissue Specificity | Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus. |
Human KCNIP1 cDNA clone(NM_001034837.1) - CDFH009632 from Creative Biomart
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Human KCNIP1 cDNA clone(NM_001034838.1) - CDFH009633 from Creative Biomart
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Human KCNIP1 cDNA clone(NM_014592.2) - CDFH009634 from Creative Biomart
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Human KCNIP1 cDNA clone(NM_014592.2) - CDFH009635 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_014592.2) - CDCR297864 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_014592.2) - CDCR297865 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_001034837.1) - CDCR343277 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_001034837.1) - CDCR343278 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_001034838.1) - CDCR343279 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_001034838.1) - CDCR343280 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_014592.2) - CDCL167712 from Creative Biomart
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Human KCNIP1 ORF Clone(NM_014592.2) - CDCR297864 from Creative biogene
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Human KCNIP1 ORF clone (NM_001034837.1) - CDCL122993 from Creative biogene
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Human KCNIP1 ORF clone (NM_001034838.1) - CDCL122995 from Creative biogene
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Human KCNIP1 cDNA Clone(NM_001034837.1) - CDFH009632 from Creative biogene
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Human KCNIP1 cDNA Clone(NM_001034838.1) - CDFH009633 from Creative biogene
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Human KCNIP1 cDNA Clone(NM_014592.2) - CDFH009634 from Creative biogene
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Human KCNIP1 cDNA Clone(NM_014592.2) - CDFH009635 from Creative biogene
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