| Gene Symbol | ACSM1 |
|---|---|
| Entrez Gene | 282576 |
| Alt Symbol | BUCS1 |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | acyl-CoA synthetase medium-chain family member 1 |
| Other Description | XL-III|XM-ligase 3|acyl-coenzyme A synthetase ACSM1, mitochondrial|butyrate--CoA ligase 1|butyryl Coenzyme A synthetase 1|butyryl-coenzyme A synthetase 1|lipoate-activating enzyme|middle-chain acyl-CoA synthetase 1|xenobiotic/medium-chain fatty acid:CoA ligase XL-3 |
| Swissprots | Q9BEA2 Q9XT43 Q9TVB5 Q32LF8 |
| Accessions | DAA15503 Q9BEA2 AB048289 BAB40420 AF126145 AAD39140 AJ132751 CAB44431 BC109602 AAI09603 XM_005224691 XP_005224748 XM_005224692 XP_005224749 NM_174682 NP_777107 |
| Function | Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro). Functions as GTP-dependent lipoate- activating enzyme that generates the substrate for lipoyltransferase. {ECO:0000269|PubMed:10561077, ECO:0000269|PubMed:11382754}. |
| Subcellular Location | Mitochondrion matrix {ECO:0000269|PubMed:10561077, ECO:0000269|PubMed:11382754}. |
| Tissue Specificity | Detected in liver. {ECO:0000269|PubMed:10561077}. |
| Top Pathways | Lipoic acid metabolism, Butanoate metabolism |