| Gene Symbol | Cd38 |
|---|---|
| Entrez Gene | 25668 |
| Alt Symbol | ADPRC 1 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | CD38 molecule |
| Other Description | 2'-phospho-ADP-ribosyl cyclase|2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase|2'-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase)|CD38H|cADPr hydrolase 1|cyclic ADP-ribose hydrolase 1 |
| Swissprots | Q64244 |
| Accessions | EDL99952 Q64244 D29646 BAA06129 D30795 BAA06457 FQ212353 XM_006251072 XP_006251134 NM_013127 NP_037259 |
| Function | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. |
| Subcellular Location | Membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Spleen, liver, heart, thymus, thyroid gland, ileum, colon, cerebellum, salivary gland, adrenal gland, jejunum, islets of Langerhans and osteoclasts. {ECO:0000269|PubMed:10477767}. |
| Top Pathways | Hematopoietic cell lineage, Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Epstein-Barr virus infection |