| Gene Symbol | TNS1 |
|---|---|
| Entrez Gene | 7145 |
| Alt Symbol | MST091, MST122, MST127, MSTP091, MSTP122, MSTP127, MXRA6, PPP1R155, TNS |
| Species | Human |
| Gene Type | protein-coding |
| Description | tensin 1 |
| Other Description | Matrix-remodelling-associated protein 6|matrix-remodelling associated 6|protein phosphatase 1, regulatory subunit 155|tensin-1 |
| Swissprots | Q4ZG71 Q9HBL0 Q6IPI5 |
| Accessions | AAX88952 EAW70582 EAW70583 EAW70584 EAW70585 EAW70586 EAW70587 Q9HBL0 AB209238 BAD92475 AF116610 AAF71035 AF172820 AAQ13614 AF173897 AAQ13644 AF176917 AAQ13661 AK001785 BAA91910 AK057328 AK300345 BAH13264 AK309785 AK310169 AL117537 CAB55983 AL706926 BC014042 AAH14042 BC033065 BC051304 AAH51304 BC063142 BC071905 AAH71905 BC107758 BC116187 AAI16188 BC116188 AAI16189 BC126910 AAI26911 BC140942 AAI40943 BE142921 BQ045472 XM_011511711 XP_011510013 XM_011511712 XP_011510014 XM_011511713 XP_011510015 XM_011511714 XP_011510016 XM_011511715 XP_011510017 XM_011511716 XP_011510018 XM_011511717 XP_011510019 XM_011511718 XP_011510020 XM_011511719 XP_011510021 XM_011511720 XP_011510022 XM_011511721 XP_011510023 XM_011511722 XP_011510024 XM_011511723 XP_011510025 XM_011511724 XP_011510026 XM_011511725 XP_011510027 XM_011511726 XP_011510028 XM_011511727 XP_011510029 XM_011511728 XP_011510030 XR_923002 NM_001308022 NP_001294951 NM_001308023 NP_001294952 NM_022648 NP_072174 |
| Function | Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. {ECO:0000269|PubMed:21768292}. |
| Subcellular Location | Cell surface {ECO:0000269|PubMed:21768292}. Cell junction, focal adhesion {ECO:0000269|PubMed:21768292}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21768292}. Note=Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner. |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11023826}. |