CENPF

Gene Symbol	CENPF
Entrez Gene	1063
Alt Symbol	CENF, PRO1779, hcp-1
Species	Human
Gene Type	protein-coding
Description	centromere protein F, 350/400kDa
Other Description	AH antigen|CENP-F kinetochore protein|cell-cycle-dependent 350K nuclear protein|centromere protein F|centromere protein F, 350/400kDa (mitosin)|centromere protein F, 350/400ka (mitosin)|kinetochore protein CENPF|mitosin
Swissprots	Q5VVM7 Q13171 P49454 Q13246
Accessions	CBX47616 EAW93350 P49454 AK307690 BC172232 AAI72232 BG680819 BQ774943 BU155312 BU662228 CD654009 U19769 AAA82889 U25725 AAA86889 U30872 AAA82935 XM_011509082 XP_011507384 XM_011509083 XP_011507385 NM_016343 NP_057427
Function	Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity ag
Subcellular Location	Cytoplasm, perinuclear region. Nucleus matrix. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Relocalizes to the kinetochore/centromere (coronal surface of the outer plate) and the spindle during mitosis. Observed in nucleus during interphase but not in the nucleolus. At metaphase becomes localized to areas including kinetochore and mitotic apparatus as well as cytoplasm. By telophase, is concentrated within the intracellular bridge at either side of the mid-body.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CENPF peptide - ab45477 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human CENPF protein fragment - ab158098 from Abcam Category Protein Source Wheat germ Species Human

CENPF / CENP-F Antibody Blocking Peptide - LS-E25425 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CENPF Protein - H00001063-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CENPF Peptide - AC21-0253-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CENP-F - H00001063-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CENP-F - H00001063-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Centromere Protein F Peptide - 45-393P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

Recombinant Centromere Protein F (CENPF) - RPA347Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Centromere Protein F (CENPF) - RPA347Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Centromere protein F(CENPF) ,partial - CSB-YP005210HU CSB-EP005210HU CSB-BP005210HU CSB-MP005210HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Centromere Protein F, Recombinant Protein - MBS2029482 from MyBioSource Category Protein Prices $190.00, $400.00, $620.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Centromere protein F (CENPF), partial, Recombinant Protein - MBS952421 from MyBioSource Category Protein Prices $1,100.00, $1,100.00, $1,330.00, $1,330.00, $1,700.00, $1,700.00, $2,155.00, $2,155.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Centromere protein F/mitosin, Peptide - MBS425369 from MyBioSource Category Protein Prices $175.00 Sizes 100 µg Species Human, Bovine

CENPF Peptide, Human - M34GP02967H from Creative Peptides Category Peptide Source Synthetic. Species Human

CENPF Immunizing peptide - orb17712 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

CENPF Recombinant Protein (OPCD02140) - OPCD02140 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant Human CENPF Protein (1759-2093 aa), His-MBP-tagged - CENPF-2743H from Creative Biomart Category Protein Source Baculovirus Species Human

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