Gene Symbol | HIST2H4A |
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Entrez Gene | 8370 |
Alt Symbol | FO108, H4, H4/n, H4F2, H4FN, HIST2H4 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 2, H4a |
Other Description | H4 histone family, member N|H4 histone, family 2|histone 2, H4a|histone H4|histone IV, family 2 |
Swissprots | Q6NWP7 P62805 Q6DRA9 A2VCL0 Q6FGB8 |
Accessions | AAA52652 AAM83108 CAA24918 CAI12560 BC019846 BC093969 AAH93969 BC108260 BC112193 AAI12194 BC146448 AAI46449 BC153063 AAI53064 CR542172 CAG46969 NM_003548 NP_003539 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone H1 (acetyl K63) peptide - ab104309 from Abcam
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Recombinant Human H4/n Protein - H00008370-Q01 from Novus Biologicals
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H4/n Recombinant Protein - H00008370-P01 from Novus Biologicals
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Human HIST2H4A protein - orb179615 from Biorbyt
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Histone H4 (11-25) Biotin Conjugated - 000-006-K77 from Rockland Immunochemicals Inc
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Histone H4 (1-15) Biotin Conjugated - 000-006-K75 from Rockland Immunochemicals Inc
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Histone H4 (16-30) Biotin Conjugated - 000-006-K78 from Rockland Immunochemicals Inc
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Histone H4 (21-35) Biotin Conjugated - 000-006-K79 from Rockland Immunochemicals Inc
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Histone H4 (26-40) Biotin Conjugated - 000-006-K80 from Rockland Immunochemicals Inc
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Histone H4 (31-45) Biotin Conjugated - 000-006-K81 from Rockland Immunochemicals Inc
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Histone H4 (36-50) Biotin Conjugated - 000-006-K82 from Rockland Immunochemicals Inc
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Histone H4 (41-55) Biotin Conjugated - 000-006-K83 from Rockland Immunochemicals Inc
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Histone H4 (46-60) Biotin Conjugated - 000-006-K84 from Rockland Immunochemicals Inc
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Histone H4 (51-65) Biotin Conjugated - 000-006-K85 from Rockland Immunochemicals Inc
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Histone H4 (56-70) Biotin Conjugated - 000-006-K86 from Rockland Immunochemicals Inc
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Histone H4 (61-75) Biotin Conjugated - 000-006-K87 from Rockland Immunochemicals Inc
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Histone H4 (6-20) Biotin Conjugated - 000-006-K76 from Rockland Immunochemicals Inc
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Histone H4 (66-80) Biotin Conjugated - 000-006-K88 from Rockland Immunochemicals Inc
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Histone H4 (71-85) Biotin Conjugated - 000-006-K89 from Rockland Immunochemicals Inc
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Histone H4 (76-90) Biotin Conjugated - 000-006-K90 from Rockland Immunochemicals Inc
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Histone H4 (81-95) Biotin Conjugated - 000-006-K91 from Rockland Immunochemicals Inc
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Histone H4 (86-100) Biotin Conjugated - 000-006-K92 from Rockland Immunochemicals Inc
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Histone H4 (90-103) Biotin Conjugated - 000-006-K93 from Rockland Immunochemicals Inc
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Histone H4, 36-50 K44Me1 - 000-001-K44 from Rockland Immunochemicals Inc
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Histone H4, 36-50 K44Me2 - 000-001-K45 from Rockland Immunochemicals Inc
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