| Gene Symbol | murF |
|---|---|
| Entrez Gene | 944813 |
| Alt Symbol | ECK0087, JW0084, mra |
| Species | Escherichia coli |
| Gene Type | protein-coding |
| Description | UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase |
| Other Description | - |
| Swissprots | P11880 P77636 O07100 |
| Accessions | AAC73197 NP_414628 |
| Function | Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. {ECO:0000255|HAMAP-Rule:MF_02019, ECO:0000269|PubMed:2186811}. |
| Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02019, ECO:0000269|PubMed:2186811}. |
| Top Pathways | Peptidoglycan biosynthesis, Vancomycin resistance, Lysine biosynthesis |