| Gene Symbol |
GNG12
|
| Entrez Gene |
55970
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), gamma 12
|
| Other Description |
G-protein gamma-12 subunit|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
|
| Swissprots |
Q9BRV5 Q69YP5 Q9UBI6
|
| Accessions |
AAF04571 CAV30706 EAX06484 EAX06485 EAX06486 Q9UBI6 AF119663 AAF17220 AF123766 AAP97245 AF365871 AAK53385 AF493879 AAM12593 AK055914 AK092014 AK223000 BAD96720 AK293101 BAF85790 AL049367 AL832431 CAH10645 BC005940 AAH05940 BC013090 BP236225 BP236699 BU151184 BU620098 JF432446 ADZ15663 XM_011541789 XP_011540091 XM_011541790 XP_011540092 XM_011541791 XP_011540093 NM_018841 NP_061329
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Top Pathways |
PI3K-Akt signaling pathway, MAPK signaling pathway, Circadian entrainment, Alcoholism, Retrograde endocannabinoid signaling
|
![Western Blot: G gamma12 Overexpression Lysate (Adult Normal) [NBL1-11172] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for G gamma12.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9019_G%2520gamma12%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11172-img0002.jpg)