| Gene Symbol | vps46 |
|---|---|
| Entrez Gene | 8616449 |
| Alt Symbol | DDBDRAFT_0189855, DDBDRAFT_0191317, DDB_0189855, DDB_0191317 |
| Species | Dictyostelium discoideum |
| Gene Type | protein-coding |
| Description | SNF7 family protein |
| Other Description | - |
| Swissprots | Q55F99 O96552 |
| Accessions | EAL73149 XM_642542 XP_647634 |
| Function | Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). {ECO:0000250}. |
| Subcellular Location | Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Top Pathways | Endocytosis |