| Gene Symbol |
IGFBP2
|
| Entrez Gene |
3485
|
| Alt Symbol |
IBP2, IGF-BP53
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
insulin-like growth factor binding protein 2, 36kDa
|
| Other Description |
IBP-2|IGF-binding protein 2|IGFBP-2|insulin-like growth factor-binding protein 2
|
| Swissprots |
Q14619 P18065 Q9UCL3
|
| Accessions |
AAA36048 AAB22308 AAQ87876 AAY14661 AAY15079 CBX47602 EAW70573 P18065 A09809 CAA00862 AB209509 BAD92746 AL559513 BC004312 AAH04312 BC009902 AAH09902 BC012769 AAH12769 BC071967 AAH71967 DQ893450 ABM84376 EU176752 ABW03553 M35410 AAA03246 X16302 CAA34373 NM_000597 NP_000588
|
| Function |
Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. {ECO:0000269|PubMed:19081843}.
|
| Subcellular Location |
Secreted.
|