Gene Symbol |
BICD2
|
Entrez Gene |
23299
|
Alt Symbol |
SMALED2, bA526D8.1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
bicaudal D homolog 2 (Drosophila)
|
Other Description |
bic-D 2|coiled-coil protein BICD2|cytoskeleton-like bicaudal D protein homolog 2|homolog of Drosophila bicaudal D|protein bicaudal D homolog 2
|
Swissprots |
Q96LH2 O75181 Q5TBQ3 Q9BT84 Q5TBQ2 Q9H561 Q8TD16
|
Accessions |
EAW62829 Q8TD16 AB014599 BAA31674 AY052562 AAL12246 BC004296 AAH04296 BC010428 AAH10428 BC073970 AAH73970 NM_001003800 NP_001003800 NM_015250 NP_056065
|
Function |
May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex (By similarity). {ECO:0000250}.
|
Subcellular Location |
Golgi apparatus. Cytoplasm, cytoskeleton. Note=In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology. {ECO:0000250}.
|
Tissue Specificity |
Ubiquitous.
|