Gene Symbol | BICD2 |
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Entrez Gene | 23299 |
Alt Symbol | SMALED2, bA526D8.1 |
Species | Human |
Gene Type | protein-coding |
Description | bicaudal D homolog 2 (Drosophila) |
Other Description | bic-D 2|coiled-coil protein BICD2|cytoskeleton-like bicaudal D protein homolog 2|homolog of Drosophila bicaudal D|protein bicaudal D homolog 2 |
Swissprots | Q96LH2 O75181 Q5TBQ3 Q9BT84 Q5TBQ2 Q9H561 Q8TD16 |
Accessions | EAW62829 Q8TD16 AB014599 BAA31674 AY052562 AAL12246 BC004296 AAH04296 BC010428 AAH10428 BC073970 AAH73970 NM_001003800 NP_001003800 NM_015250 NP_056065 |
Function | May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus. Cytoplasm, cytoskeleton. Note=In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology. {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
BICD2 CRISPR/Cas9 KO Plasmid (h) - sc-405525 from Santa Cruz Biotechnology
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BICD2 HDR Plasmid (h) - sc-405525-HDR from Santa Cruz Biotechnology
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BICD2 Double Nickase Plasmid (h) - sc-405525-NIC from Santa Cruz Biotechnology
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BICD2 Double Nickase Plasmid (h2) - sc-405525-NIC-2 from Santa Cruz Biotechnology
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BICD2 CRISPR Activation Plasmid (h) - sc-405525-ACT from Santa Cruz Biotechnology
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BICD2 CRISPR Activation Plasmid (h2) - sc-405525-ACT-2 from Santa Cruz Biotechnology
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BICD2 Lentiviral Activation Particles (h) - sc-405525-LAC from Santa Cruz Biotechnology
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BICD2 Lentiviral Activation Particles (h2) - sc-405525-LAC-2 from Santa Cruz Biotechnology
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BICD2 siRNA (h) - sc-92831 from Santa Cruz Biotechnology
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BICD2 shRNA Plasmid (h) - sc-92831-SH from Santa Cruz Biotechnology
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BICD2 shRNA (h) Lentiviral Particles - sc-92831-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN3975 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3975 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR14185 from Sigma-Aldrich
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BICD2 siRNA (Human) - CRH8159 from Cohesion Biosciences
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BICD2 - MBS8235386 from MyBioSource
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BICD2 CRISPR/Cas9 KO Plasmid (h2) - sc-405525-KO-2 from Santa Cruz Biotechnology
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BICD2 HDR Plasmid (h2) - sc-405525-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human BICD2 (NM_015250.3) - SHH246678 from Creative biogene
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shRNA set against Human BICD2(NM_001003800.1) - SHG100477 from Creative biogene
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shRNA set against Human BICD2(NM_015250.3) - SHG100513 from Creative biogene
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Human BICD2 siRNA - orb268661 from Biorbyt
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BICD2 shRNA Plasmid (Human) - CHH8159 from Cohesion Biosciences
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BICD2 miRNA 3'UTR clone - MiUTR1H-00888 from Creative biogene
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BICD2 miRNA 3'UTR clone - MiUTR4H-TG00791 from Creative biogene
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