Gene Symbol | SPRR1B |
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Entrez Gene | 6699 |
Alt Symbol | CORNIFIN, GADD33, SPRR1 |
Species | Human |
Gene Type | protein-coding |
Description | small proline-rich protein 1B |
Other Description | 14.9 kDa pancornulin|SPR-IB|cornifin B|cornifin-B|small proline-rich protein IB |
Swissprots | B2R5H7 P22530 P22529 Q5T524 P22528 |
Accessions | AAA36643 AAV40826 EAW53351 P22528 AK312191 BAG35124 BC056240 AAH56240 BC156326 AAI56327 BC157076 AAI57077 CK300778 DQ323996 ABC88598 M19888 AAA36636 M21300 AAA36637 M21301 AAA36638 NM_003125 NP_003116 |
Function | Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea. |
Anti-SPRR1b antibody - ab123237 from Abcam
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Anti-SPRR1b antibody - ab94961 from Abcam
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89, AP) - LS-C207675 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89, APC) - LS-C207676 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89, Biotin) - LS-C207677 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89, FITC) - LS-C209053 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89, PE) - LS-C209056 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89, Azide-free, HRP) - LS-C209055 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89) - LS-C325353 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (C-Terminus) - LS-C146187 from LifeSpan Bioscience
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Anti-CORNIFIN / SPRR1B Antibody (aa60-89) - LS-C161474 from LifeSpan Bioscience
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ANTI-SPRR1B (C-TERM) antibody produced in rabbit - SAB1301567 from Sigma-Aldrich
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Anti-SPRR1B antibody produced in rabbit - SAB2107798 from Sigma-Aldrich
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SPRR1B antibody - middle region (ARP63557_P050) - ARP63557_P050 from Aviva Systems Biology
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SPRR1B-Antibody-C-term - AP9052b from Abgent, a WuXi AppTec company
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SPRR1B Antibody - C-terminal region (OAAB05639) - OAAB05639 from Aviva Systems Biology
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SPRR1B Antibody - abx034208 from Abbexa
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SPRR1B / Cornifin-B antibody - 11959-1-AP from Acris Antibodies
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SPRR1B / Cornifin-B (C-term) antibody - AP54033PU-N from Acris Antibodies
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Rabbit Anti-Human SPRR1B (C-term) - 102-18125 from RayBiotech
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SPRR1B antibody (C-term) - STJ51733 from St John's Laboratory Ltd
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SPRR1B antibody - 11959-1-AP from Proteintech Group
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SPRR1B Antibody - GWB-MW909I from Genway Biotech
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Anti-SPRR1B (aa 48-89) polyclonal antibody - DPABH-21340 from Creative Diagnostics
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Anti-SPRR1B monoclonal antibody - DCABH-16963 from Creative Diagnostics
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