Gene Symbol | SPRR1B |
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Entrez Gene | 6699 |
Alt Symbol | CORNIFIN, GADD33, SPRR1 |
Species | Human |
Gene Type | protein-coding |
Description | small proline-rich protein 1B |
Other Description | 14.9 kDa pancornulin|SPR-IB|cornifin B|cornifin-B|small proline-rich protein IB |
Swissprots | B2R5H7 P22530 P22529 Q5T524 P22528 |
Accessions | AAA36643 AAV40826 EAW53351 P22528 AK312191 BAG35124 BC056240 AAH56240 BC156326 AAI56327 BC157076 AAI57077 CK300778 DQ323996 ABC88598 M19888 AAA36636 M21300 AAA36637 M21301 AAA36638 NM_003125 NP_003116 |
Function | Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea. |
Human SPRR1b full length protein - ab167925 from Abcam
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Human SPRR1b full length protein - ab114941 from Abcam
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CORNIFIN / SPRR1B Antibody Blocking Peptide - LS-E23182 from LifeSpan Bioscience
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CORNIFIN / SPRR1B Antibody Blocking Peptide - LS-E9917 from LifeSpan Bioscience
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Recombinant Human SPRR1B Protein - H00006699-P01 from Novus Biologicals
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SPRR1B-Antibody-C-term-Blocking-Peptide - BP9052b from Abgent, a WuXi AppTec company
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Human SPRR1B protein - orb191234 from Biorbyt
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SPRR1B / Cornifin-B - H00006699-P01-10 from Acris Antibodies
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SPRR1B / Cornifin-B - H00006699-P01-25 from Acris Antibodies
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SPRR1B fusion protein - Ag2563 from Proteintech Group
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Recombinant Human SPRR1B - SPRR1B-30402TH from Creative Biomart
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Recombinant Human SPRR1B, GST-tagged - SPRR1B-2933H from Creative Biomart
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Recombinant Human Cornifin-B(SPRR1B) - CSB-YP022611HU CSB-EP022611HU CSB-BP022611HU CSB-MP022611HU from Cusabio
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SPRR1B Peptide, Human - M34GP15094H from Creative Peptides
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Cornifin-B (SPRR1B), Recombinant Protein - MBS966064 from MyBioSource
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Small Proline-Rich Protein 1B, Recombinant Protein - MBS145745 from MyBioSource
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