CBX4

Gene Symbol	CBX4
Entrez Gene	8535
Alt Symbol	NBP16, PC2
Species	Human
Gene Type	protein-coding
Description	chromobox homolog 4
Other Description	E3 SUMO-protein ligase CBX4|NS5ATP1-binding protein 16|Pc class 2 homolog|chromobox homolog 4 (Pc class homolog, Drosophila)|chromobox protein homolog 4|polycomb 2 homolog
Swissprots	Q96C04 Q6TPI8 B1PJR7 O00257
Accessions	EAW89572 EAW89573 O00257 AF013956 AAB80718 AI796748 AY390430 AAQ97596 BC014967 AAH14967 BG029608 BQ225831 EU439707 ACA49234 U94344 AAB62734 XM_011525399 XP_011523701 NM_003655 NP_003646
Function	E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.
Subcellular Location	Nucleus. Nucleus speckle. Note=Localization to nuclear polycomb bodies is required for ZNF131 sumoylation.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MPc2 CRISPR/Cas9 KO Plasmid (h) - sc-403903 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 HDR Plasmid (h) - sc-403903-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 Double Nickase Plasmid (h) - sc-403903-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 Double Nickase Plasmid (h2) - sc-403903-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 CRISPR Activation Plasmid (h) - sc-403903-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 CRISPR Activation Plasmid (h2) - sc-403903-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 Lentiviral Activation Particles (h) - sc-403903-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 Lentiviral Activation Particles (h2) - sc-403903-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MPc2 siRNA (h) - sc-38193 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MPc2 shRNA Plasmid (h) - sc-38193-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MPc2 shRNA (h) Lentiviral Particles - sc-38193-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CBX4 RNAi - H00008535-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN5428 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5428 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06371 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr06371

CBX4 siRNA (Human) - CRH5606 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CBX4 - MBS827601 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CBX4 (NM_003655.2) - SHH255521 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CBX4(NM_003655.2) - SHG145441 from Creative biogene Category siRNA Species Reactivities Human

CBX4 siRNA (h2) - sc-270615 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CBX4 shRNA Plasmid (h2) - sc-270615-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CBX4 shRNA (h2) Lentiviral Particles - sc-270615-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CBX4 shRNA Plasmid (Human) - CHH5606 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CBX4 miRNA 3'UTR clone - MiUTR1H-01710 from Creative biogene Species Reactivities Human

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