Gene Symbol | HSPB8 |
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Entrez Gene | 26353 |
Alt Symbol | CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22 |
Species | Human |
Gene Type | protein-coding |
Description | heat shock 22kDa protein 8 |
Other Description | E2-induced gene 1 protein|alpha-crystallin C chain|heat shock 27kDa protein 8|heat shock protein beta-8|protein kinase H11|small stress protein-like protein HSP22 |
Swissprots | Q9UKS3 B2R6A6 Q9UJY1 Q6FIH3 |
Accessions | EAW98144 Q9UJY1 AF133207 AAD55359 AF191017 AAF09481 AF217987 AAG17230 AF250138 AAF65562 AK001825 AK312501 BAG35403 AL136936 CAB66870 BC002673 AAH02673 BT006876 AAP35522 CR533453 CAG38484 DQ896404 ABM87403 EU176429 ABW03880 NM_014365 NP_055180 |
Function | Displays temperature-dependent chaperone activity. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19464326}. Nucleus {ECO:0000269|PubMed:19464326}. Note=Translocates to nuclear foci during heat shock. |
Tissue Specificity | Predominantly expressed in skeletal muscle and heart. {ECO:0000269|PubMed:11470154}. |
αC-crystallin CRISPR/Cas9 KO Plasmid (h) - sc-408216 from Santa Cruz Biotechnology
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αC-crystallin HDR Plasmid (h) - sc-408216-HDR from Santa Cruz Biotechnology
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αC-crystallin Double Nickase Plasmid (h) - sc-408216-NIC from Santa Cruz Biotechnology
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αC-crystallin Double Nickase Plasmid (h2) - sc-408216-NIC-2 from Santa Cruz Biotechnology
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αC-crystallin CRISPR Activation Plasmid (h) - sc-408216-ACT from Santa Cruz Biotechnology
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αC-crystallin CRISPR Activation Plasmid (h2) - sc-408216-ACT-2 from Santa Cruz Biotechnology
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αC-crystallin Lentiviral Activation Particles (h) - sc-408216-LAC from Santa Cruz Biotechnology
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αC-crystallin Lentiviral Activation Particles (h2) - sc-408216-LAC-2 from Santa Cruz Biotechnology
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αC-crystallin siRNA (h) - sc-72422 from Santa Cruz Biotechnology
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αC-crystallin shRNA Plasmid (h) - sc-72422-SH from Santa Cruz Biotechnology
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αC-crystallin shRNA (h) Lentiviral Particles - sc-72422-V from Santa Cruz Biotechnology
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HSPB8/HSP22 RNAi - H00026353-R01V from Novus Biologicals
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HSPB8/HSP22 RNAi - H00026353-R02 from Novus Biologicals
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MISSION® esiRNA - EHU160791 from Sigma-Aldrich
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MISSION® siRNA - SIHK0925 from Sigma-Aldrich
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MISSION® siRNA - SIHK0924 from Sigma-Aldrich
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MISSION® siRNA - SIHK0923 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10377 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10377 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07236 from Sigma-Aldrich
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HSPB8 siRNA (Human) - CRH8820 from Cohesion Biosciences
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HSPB8 - MBS8237588 from MyBioSource
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shRNA set against Human HSPB8 (NM_014365.2) - SHH315717 from Creative biogene
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shRNA set against Human HSPB8(NM_014365.2) - SHH134687 from Creative biogene
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Human HSPB8 siRNA - orb269322 from Biorbyt
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