Gene Symbol | FPGT |
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Entrez Gene | 8790 |
Alt Symbol | GFPP |
Species | Human |
Gene Type | protein-coding |
Description | fucose-1-phosphate guanylyltransferase |
Other Description | GDP-L-fucose diphosphorylase|GDP-beta-L-fucose pyrophosphorylase|fucose-1-phosphate guanyltransferase |
Swissprots | Q8N5J7 E9PNQ2 B4E2Y7 B4DRX2 O14772 A6NMH3 |
Accessions | AAC82511 EAX06417 O14772 AF017445 AAC73005 AI025848 AK223254 BAD96974 AK294948 BAG58023 AK299468 BAG61434 AK304490 BAG65299 BC020720 AAH20720 BC032308 AAH32308 CR743704 DB066016 NM_001199328 NP_001186257 NM_001199329 NP_001186258 NM_003838 NP_003829 |
Function | Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed in many tissues. |
Top Pathways | Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism |
FPGT siRNA (h) - sc-75055 from Santa Cruz Biotechnology
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FPGT shRNA Plasmid (h) - sc-75055-SH from Santa Cruz Biotechnology
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FPGT shRNA (h) Lentiviral Particles - sc-75055-V from Santa Cruz Biotechnology
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FPGT RNAi - H00008790-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN8924 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8924 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10263 from Sigma-Aldrich
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FPGT siRNA (Human) - CRH5791 from Cohesion Biosciences
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FPGT - MBS8212996 from MyBioSource
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shRNA set against Human FPGT (NM_003838.3) - SHH296929 from Creative biogene
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FPGT shRNA Plasmid (Human) - CHH5791 from Cohesion Biosciences
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FPGT miRNA 3'UTR clone - MiUTR3H-06116 from Creative biogene
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