| Gene Symbol | SOS1 |
|---|---|
| Entrez Gene | 6654 |
| Alt Symbol | GF1, GGF1, GINGF, HGF, NS4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | son of sevenless homolog 1 (Drosophila) |
| Other Description | SOS-1|gingival fibromatosis, hereditary, 1|guanine nucleotide exchange factor|son of sevenless homolog 1 |
| Swissprots | Q07889 A8K2G3 B4DXG2 |
| Accessions | AAF04460 AAM22406 AAX93186 AAY24202 CBX55730 EAX00350 EAX00351 EAX00352 EAX00353 Q07889 AB209140 BAD92377 AK290228 BAF82917 AK301960 BAG63374 AL833457 AV702692 BC140215 AAI40216 L13857 AAA35913 XM_005264515 XP_005264572 XM_011533060 XP_011531362 XM_011533061 XP_011531363 XM_011533062 XP_011531364 XM_011533063 XP_011531365 XM_011533064 XP_011531366 XM_011533065 XP_011531367 XM_011533066 XP_011531368 NM_005633 NP_005624 |
| Function | Promotes the exchange of Ras-bound GDP by GTP. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity). {ECO:0000250}. |
| Tissue Specificity | Expressed in gingival tissues. {ECO:0000269|PubMed:11868160}. |
| Top Pathways | Alcoholism, Prolactin signaling pathway, PI3K-Akt signaling pathway, MicroRNAs in cancer, Estrogen signaling pathway |