CADPS2

Gene Symbol CADPS2
Entrez Gene 93664
Alt Symbol -
Species Human
Gene Type protein-coding
Description Ca++-dependent secretion activator 2
Other Description CAPS-2|Ca2+-dependent activator protein for secretion 2|calcium-dependent activator protein for secretion 2|calcium-dependent secretion activator 2
Swissprots Q8N7M4 Q86UW7 Q8IZW9 Q9HCI1 Q7Z5T7 B7ZM56 Q9H6P4 Q9NWK8 A4D0X3 Q658Q2
Accessions CCQ43023 CCQ43024 EAL24339 EAW83571 EAW83572 EAW83573 EAW83574 EAW83575 EAW83576 Q86UW7 AB046811 BAB13417 AF401638 AAN38707 AK000768 BAA91372 AK025672 BAB15210 AK054853 BAG51434 AK126518 BAG54341 AL833058 CAH56288 AY264289 AAP22132 BC054339 AAH54339 BC136601 AAI36602 BC144278 AAI44279 BC144279 AAI44280 BX110721 DA118516 DA248542 DA323097 KJ534798 AHW56438 KJ534799 AHW56439 KJ534800 AHW56440 KJ534801 AHW56441 KJ534802 AHW56442 KJ534803 AHW56443 KJ534804 AHW56444 KJ534805 AHW56445 KJ535060 AHW56699 XM_005250695 XP_005250752 XM_005250696 XP_005250753 XM_005250697 XP_005250754 XM_005250698 XP_005250755 XM_005250699 XP_005250756 XM_005250700 XP_005250757 XM_005250701 XP_005250758 XM_005250702 XP_005250759 XM_005250703 XP_005250760 XM_005250704 XP_005250761 XM_005250705 XP_005250762 XM_005250706 XP_005250763 XM_005250707 XP_005250764 XM_005250708 XP_005250765 XM_011516695 XP_011514997 XM_011516696 XP_011514998 XM_011516697 XP_011514999 NM_001009571 NP_001009571 NM_001167940 NP_001161412 NM_017954 NP_060424
Function Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)- dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasmic vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell junction, synapse. Note=Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Probably localizes to different vesicles compared to CADPS. Enriched on vesicular structures in the parallel fiber terminal of granule cells that are distinct from synaptic vesicles.
Tissue Specificity Widely expressed. Expressed in all adult and fetal tissues examined, with the strongest expression in kidney and pancreas. In brain, it is expressed at high levels in cerebellum, to a lesser degree in cerebral cortex, occipital pole, and frontal and temporal lobes. Only weakly expressed in medulla, spinal cord and putamen. {ECO:0000269|PubMed:12659812}.

CAPS-2 (H-57) - sc-135029 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CAPS-2 (H-57): sc-135029. Western blot analysis of CAPS-2 expression in Caki-1 whole cell lysate.

CAPS-2 (S-15) - sc-65015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CAPS-2 (P-20) - sc-65014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CAPS-2 (P-20): sc-65014. Western blot analysis of CAPS-2 expression in HEK293 (A), Jurkat (B) and K-562 (C) whole cell lysates.

Anti-CADPS2 antibody - ab69794 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CADPS2 antibody (ab69794) at 0.5 µg/mlLane 2 : Anti-CADPS2 antibody (ab69794) at 1 µg/mlLane 1 : Human brain tissue lysateLane 2 : Human brain tissue lysateLysates/proteins at 15 µg per lane.

CAPS2 Antibody - NBP1-76898 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CAPS2 Antibody [NBP1-76898] - Human brain tissue lysate with CAPS2 antibody at (A) 0.5 and (B) 1 ug/ml.

CADPS2 Polyclonal Antibody - bs-11500R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11500R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11500R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11500R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11500R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, Cy3 Conjugated - bs-11500R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, Cy5 Conjugated - bs-11500R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11500R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, Cy7 Conjugated - bs-11500R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, FITC Conjugated - bs-11500R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, Biotin Conjugated - bs-11500R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CADPS2 Polyclonal Antibody, HRP Conjugated - bs-11500R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CAPS2 antibody produced in rabbit - PRS4565 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CAPS2: <B>Cat. No. PRS4565</B> Immunohistochemistry of CAPS2 in human brain with CAPS2 antibody at 5 μg/mL.

CAPS2 antibody - GTX85405 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-CAPS2 antibody used in Immunohistochemistry. GTX85405
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