| Gene Symbol | hspB |
|---|---|
| Entrez Gene | 8617589 |
| Alt Symbol | DDBDRAFT_0190878, DDBDRAFT_0191168, DDB_0190878, DDB_0191168 |
| Species | Dictyostelium discoideum |
| Gene Type | protein-coding |
| Description | heat shock cognate protein Hsc70-1 |
| Other Description | heat shock protein |
| Swissprots | Q55C64 P36415 |
| Accessions | EAL71922 Q55C64 XM_641525 XP_646617 |
| Function | Affects actin polymerization through interaction with the actin-binding protein CAP32/34 (acpA/acpB). Acts as a chaperone by stimulating the refolding of denaturated acpA and acpB, but neither stimulates nor inhibits the capping activity of native CAP32/34. {ECO:0000269|PubMed:8404847, ECO:0000269|PubMed:8982279}. |
| Subcellular Location | Cytoplasm. Note=Found in F-actin-rich regions of the cell cortex and cell protrusions. |
| Top Pathways | Endocytosis, Spliceosome, Protein processing in endoplasmic reticulum |