Gene Symbol | RAMP1 |
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Entrez Gene | 10267 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | receptor (G protein-coupled) activity modifying protein 1 |
Other Description | CRLR activity-modifying protein 1|calcitonin receptor-like receptor activity modifying protein 1|calcitonin-receptor-like receptor activity-modifying protein 1|receptor (calcitonin) activity modifying protein 1|receptor activity modifying protein 1|receptor activity-modifying protein 1 |
Swissprots | O60894 Q6FGS5 |
Accessions | AAY14674 AAY24219 EAW71127 O60894 AI017108 AJ001014 CAA04472 AY265457 AAP23298 BC000548 AAH00548 BI548986 BM126103 BM978161 BX327017 CR542032 CAG46829 CR542044 CAG46841 DQ891905 ABM82831 DQ895091 ABM86017 XM_011510477 XP_011508779 XM_011510478 XP_011508780 NM_001308353 NP_001295282 NM_005855 NP_005846 |
Function | Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL. {ECO:0000269|PubMed:9620797}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract. {ECO:0000269|PubMed:9620797}. |
Top Pathways | Vascular smooth muscle contraction |
RAMP1 CRISPR/Cas9 KO Plasmid (h) - sc-401396 from Santa Cruz Biotechnology
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RAMP1 HDR Plasmid (h) - sc-401396-HDR from Santa Cruz Biotechnology
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RAMP1 Double Nickase Plasmid (h) - sc-401396-NIC from Santa Cruz Biotechnology
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RAMP1 Double Nickase Plasmid (h2) - sc-401396-NIC-2 from Santa Cruz Biotechnology
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RAMP1 CRISPR Activation Plasmid (h) - sc-401396-ACT from Santa Cruz Biotechnology
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RAMP1 CRISPR Activation Plasmid (h2) - sc-401396-ACT-2 from Santa Cruz Biotechnology
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RAMP1 Lentiviral Activation Particles (h) - sc-401396-LAC from Santa Cruz Biotechnology
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RAMP1 Lentiviral Activation Particles (h2) - sc-401396-LAC-2 from Santa Cruz Biotechnology
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RAMP1 siRNA (h) - sc-40894 from Santa Cruz Biotechnology
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RAMP1 shRNA Plasmid (h) - sc-40894-SH from Santa Cruz Biotechnology
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RAMP1 shRNA (h) Lentiviral Particles - sc-40894-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU036681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17932 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17932 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02538 from Sigma-Aldrich
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RAMP1 siRNA (Human) - CRH6950 from Cohesion Biosciences
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RAMP1 RNAi - H00010267-R01 from Novus Biologicals
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RAMP1 - MBS8218107 from MyBioSource
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shRNA set against Human RAMP1 (NM_005855.2) - SHH389400 from Creative biogene
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shRNA set against Human RAMP1(NM_005855.2) - SHR163884 from Creative biogene
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RAMP1 shRNA Plasmid (Human) - CHH6950 from Cohesion Biosciences
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RAMP1 miRNA 3'UTR clone - MiUTR1H-08613 from Creative biogene
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