FUS

Gene Symbol FUS
Entrez Gene 2521
Alt Symbol ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS
Species Human
Gene Type protein-coding
Description FUS RNA binding protein
Other Description 75 kDa DNA-pairing protein|RNA-binding protein FUS|fus-like protein|fused in sarcoma|fusion gene in myxoid liposarcoma|heterogeneous nuclear ribonucleoprotein P2|oncogene FUS|oncogene TLS|translocated in liposarcoma protein
Swissprots Q9H4A8 P35637
Accessions AAC35284 AAC35285 CAD82835 EAW52150 EAW52151 EAW52152 P35637 AB208902 BAD92139 AI333366 AK098774 AK130774 AK290936 BAF83625 AK299129 BAG61182 AK301110 BAG62709 AW408771 AW514140 BC000402 AAH00402 BC002459 AAH02459 BC026062 AAH26062 BC051293 BT007131 AAP35795 BX423519 CR456747 CAG33028 DA541747 DC361263 DQ891705 ABM82631 DQ894882 ABM85808 GU933437 R07006 S62140 AAB27102 U00942 U36561 AAA79948 X71428 CAA50559 XM_005255233 XP_005255290 XM_011545781 XP_011544083 XM_011545782 XP_011544084 NM_001170634 NP_001164105 NM_001170937 NP_001164408 NM_004960 NP_004951 NR_028388 NM_001010850
Function Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.
Subcellular Location Nucleus {ECO:0000269|PubMed:19251627, ECO:0000269|PubMed:19251628}.
Tissue Specificity Ubiquitous.
Top Pathways Transcriptional misregulation in cancer

FUS/TLS CRISPR/Cas9 KO Plasmid (h) - sc-400612 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS HDR Plasmid (h) - sc-400612-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS Double Nickase Plasmid (h) - sc-400612-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS Double Nickase Plasmid (h2) - sc-400612-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS CRISPR Activation Plasmid (h) - sc-400612-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS CRISPR Activation Plasmid (h2) - sc-400612-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS Lentiviral Activation Particles (h) - sc-400612-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS Lentiviral Activation Particles (h2) - sc-400612-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUS/TLS siRNA (h) - sc-40563 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FUS/TLS shRNA Plasmid (h) - sc-40563-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FUS/TLS shRNA (h) Lentiviral Particles - sc-40563-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FUS RNAi - H00002521-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU092111 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1385 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1386 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1385 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1386 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02583 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02583

FUS siRNA (Human) - CRH1667 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FUS RNAi - H00002521-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FUS - MBS8200823 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FUS (NM_004960.3) - SHH297733 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FUS(NM_004960.3) - SHH070229 from Creative biogene

Category siRNA
Species Reactivities Human

Human FUS siRNA - orb262169 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FUS shRNA Plasmid (Human) - CHH1667 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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