| Gene Symbol | Sar1a |
|---|---|
| Entrez Gene | 20224 |
| Alt Symbol | 1600019H17Rik, Sara, Sara1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | SAR1 gene homolog A (S. cerevisiae) |
| Other Description | GTP-binding protein SAR1a|SAR1a gene homolog 1 |
| Swissprots | P36536 |
| Accessions | EDL32130 EDL32131 EDL32132 EDL32133 EDL32134 EDL32135 EDL32136 P36536 AK003538 AK005495 AK157843 BAE34224 AK159239 BAE34922 AK168175 BAE40135 AK178688 AK190267 AK192256 AK194825 AK202050 AK203047 AK206663 AK208660 AK210154 AK210524 BC005549 AAH05549 L20294 AAA16323 XM_006513398 XP_006513461 XM_006513399 XP_006513462 XM_006513401 XP_006513464 XM_011243389 XP_011241691 NM_009120 NP_033146 |
| Function | Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). {ECO:0000250}. |
| Subcellular Location | Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. |
| Tissue Specificity | Expressed in most tissues including liver, heart, brain, skeletal muscle and kidney. |
| Top Pathways | Protein processing in endoplasmic reticulum, Legionellosis |