Lorcainide HCl inhibits NaV1.7 channels expressed in HEK293 cells. A: Time course of current reversible inhibition by 50 µM Lorcainide HCl (ab141821). Currents were elicited by a voltage ramp from a holding potential of -100 mV to 60 mV (30 ms) delivered every 10 seconds. B: Example traces of current response to voltage ramp stimulation before and during 50 µM Lorcainide HCl application.

Lorcainide HCl inhibits NaV1.7 channels expressed in HEK293 cells. A: Time course of current reversible inhibition by 50 µM Lorcainide HCl (ab141821). Currents were elicited by a voltage ramp from a holding potential of -100 mV to 60 mV (30 ms) delivered every 10 seconds. B: Example traces of current response to voltage ramp stimulation before and during 50 µM Lorcainide HCl application.


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