Phrixotoxin-3 inhibits NaV1.2 channels heterologously expressed in Xenopus oocytes. Superimposed traces of NaV1.2 currents before (green) and during (black) application of 300 nM Phrixotoxin-3 (ab141845). Currents were elicited from a holding potential of -100 mV and test pulses of 35 ms to +60 mV were delivered every 5 sec.

Phrixotoxin-3 inhibits NaV1.2 channels heterologously expressed in Xenopus oocytes. Superimposed traces of NaV1.2 currents before (green) and during (black) application of 300 nM Phrixotoxin-3 (ab141845). Currents were elicited from a holding potential of -100 mV and test pulses of 35 ms to +60 mV were delivered every 5 sec.


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