Amlodipine besylate blocks L-type Ca2+ currents in Xenopusoocytes. A. Time course of L-type channel (CaV1.2+a2d1+ß1a) activity before and during applications of 100 µM Amlodipine besylate (ab141777; green) and upon wash. Holding potential was -100 mV and currents were elicited every 10 seconds by 100 ms steps to 0 mV. B. Example current traces before (black) and during application of 100 µM Amlodipine besylate (taken from the experiment described in A).

Amlodipine besylate blocks L-type Ca2+ currents in Xenopusoocytes. A. Time course of L-type channel (CaV1.2+a2d1+ß1a) activity before and during applications of 100 µM Amlodipine besylate (ab141777; green) and upon wash. Holding potential was -100 mV and currents were elicited every 10 seconds by 100 ms steps to 0 mV. B. Example current traces before (black) and during application of 100 µM Amlodipine besylate (taken from the experiment described in A).


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