Recombinant Human GDF-15, CF

• Supplier: R&D Systems
• Catalog: 957-GD-025/CF
• Category: Protein
• Nature: Recombinant
• Source: Chinese Hamster Ovary cell line, CHO-derived, Ala197-Ile308, with an N-terminal 6-His tag
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: Q99988
• Gene: GDF15

Product References

GDF-15 prevents platelet integrin activation and thrombus formation. - GDF-15 prevents platelet integrin activation and thrombus formation.

Rossaint J, Vestweber D, Zarbock A. J Thromb Haemost. 2013 Feb;11(2):335-44.

Growth differentiation factor-15 suppresses maturation and function of dendritic - Growth differentiation factor-15 suppresses maturation and function of dendritic

Zhou Z, Li W, Song Y, Wang L, Zhang K, Yang J, Zhang W, Su H, Zhang Y. PLoS One. 2013 Nov 13;8(11):e78618.

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice - Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice

Schledzewski K, Geraud C, Arnold B, Wang S, Grone HJ, Kempf T, Wollert KC, Straub BK, Schirmacher P, Demory A, Schonhaber H, Gratchev A, Dietz L, Thierse HJ, Kzhyshkowska J, Goerdt S. J Clin Invest. 2011 Feb;121(2):703-14.

Growth differentiation factor 15 is induced by hepatitis C virus infection and - Growth differentiation factor 15 is induced by hepatitis C virus infection and

Si Y, Liu X, Cheng M, Wang M, Gong Q, Yang Y, Wang T, Yang W. PLoS One. 2011;6(5):e19967.

Wild-type p53 attenuates cancer cell motility by inducing growth differentiation - Wild-type p53 attenuates cancer cell motility by inducing growth differentiation

Cheng JC, Chang HM, Leung PC. Endocrinology. 2011 Aug;152(8):2987-95.

Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its - Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its

Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV. J Biol Chem. 2011 Aug 26;286(34):30034-46.

Macrophage inhibitory cytokine-1 regulates melanoma vascular development. - Macrophage inhibitory cytokine-1 regulates melanoma vascular development.

Huh SJ, Chung CY, Sharma A, Robertson GP. Am J Pathol. 2010 Jun;176(6):2948-57.

Identification of macrophage inhibitory cytokine-1 in adipose tissue and its - Identification of macrophage inhibitory cytokine-1 in adipose tissue and its

Ding Q, Mracek T, Gonzalez-Muniesa P, Kos K, Wilding J, Trayhurn P, Bing C. Endocrinology. 2009 Apr;150(4):1688-96.

Growth differentiation factor-15 as a prognostic marker in patients with acute - Growth differentiation factor-15 as a prognostic marker in patients with acute

Khan SQ, Ng K, Dhillon O, Kelly D, Quinn P, Squire IB, Davies JE, Ng LL. Eur Heart J. 2009 May;30(9):1057-65.

Progressive postnatal motoneuron loss in mice lacking GDF-15. - Progressive postnatal motoneuron loss in mice lacking GDF-15.

Strelau J, Strzelczyk A, Rusu P, Bendner G, Wiese S, Diella F, Altick AL, von Bartheld CS, Klein R, Sendtner M, Unsicker K. J Neurosci. 2009 Oct 28;29(43):13640-8.