Recombinant Mouse IL-27 (NS0-expressed), CF

• Supplier: R&D Systems
• Catalog: 2799-ML-010/CF
• Category: Protein
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: O35228 (EBI3) & Q8K3I6 (p28)
• Gene: IL27

Product References

IL-6 activates STAT5 in T cells. - IL-6 activates STAT5 in T cells.

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Interleukin-27 and interferon-gamma are involved in regulation of autoimmune - Interleukin-27 and interferon-gamma are involved in regulation of autoimmune

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Essential role for IL-27 receptor signaling in prevention of Th1-mediated - Essential role for IL-27 receptor signaling in prevention of Th1-mediated

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Expression of WSX1 in tumors sensitizes IL-27 signaling-independent natural - Expression of WSX1 in tumors sensitizes IL-27 signaling-independent natural

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Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and - Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and

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Amelioration of delayed-type hypersensitivity responses by IL-27 administration. - Amelioration of delayed-type hypersensitivity responses by IL-27 administration.

Miyazaki Y, Shimanoe Y, Wang S, Yoshida H. Biochem Biophys Res Commun. 2008 Aug 29;373(3):397-402. doi:

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation - The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation

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Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase - Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase

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