Recombinant Mouse IL-18/IL-1F4 Protein, CF

• Supplier: R&D Systems
• Catalog: B004-2
• Category: Protein
• Prices: $1,439.00
• Sizes: 200 µg
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: E. coli -derived 36-192 aa
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.
• Bioactivity: Induction of IFN-gamma by mouse IL-18 receptor transfected KG-1 cell [human myelomonocyte; ATCC CCL246] in response to the recombinant mouse IL-18 was measured using human IFN-gamma ELISA. The activity of lot 040 was as follows: IL-18 final concentration 5 ng/mL; IFN-gamma induction 2863 IU/mL and IL-18 final concentration 10 ng/mL; IFN-gamma induction 7312 IU/mL.
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• Gene: IL18

Product References

Interleukin-22 induces interleukin-18 expression from epithelial cells during - Interleukin-22 induces interleukin-18 expression from epithelial cells during

Munoz M, Eidenschenk C, Ota N, Wong K, Lohmann U, Kuhl AA, Wang X, Manzanillo P, Li Y, Rutz S, Zheng Y, Diehl L, Kayagaki N, van Lookeren-Campagne M, Liesenfeld O, Heimesaat M, Ouyang W. Immunity. 2015 Feb 17;42(2):321-31.

IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced - IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced

Antonopoulos C, Cumberbatch M, Mee JB, Dearman RJ, Wei XQ, Liew FY, Kimber I, Groves RW. J Leukoc Biol. 2008 Feb;83(2):361-7. Epub 2007 Nov 5.

STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production - STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production

Morinobu A, Gadina M, Strober W, Visconti R, Fornace A, Montagna C, Feldman GM, Nishikomori R, O'Shea JJ. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12281-6. Epub 2002 Sep 4.