Recombinant Human Serpin E2/PN1, CF

• Supplier: R&D Systems
• Catalog: 2980-PI-010
• Category: Protein
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived, Met1-Pro397, with a C-terminal 10-His tag
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• SwissProt/Accession: NP_001130000
• Gene: SERPINE2

Product References

Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 - Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2

Szabo R, Uzzun Sales K, Kosa P, Shylo NA, Godiksen S, Hansen KK, Friis S, Gutkind JS, Vogel LK, Hummler E, Camerer E, Bugge TH. PLoS Genet. 2012;8(8):e1002937.

Matriptase initiates activation of epidermal pro-kallikrein and disease onset in - Matriptase initiates activation of epidermal pro-kallikrein and disease onset in

Sales KU, Masedunskas A, Bey AL, Rasmussen AL, Weigert R, List K, Szabo R, Overbeek PA, Bugge TH. Nat Genet. 2010 Aug;42(8):676-83.

Prostasin expression is regulated by airway surface liquid volume and is - Prostasin expression is regulated by airway surface liquid volume and is

Myerburg MM, McKenna EE, Luke CJ, Frizzell RA, Kleyman TR, Pilewski JM. Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L932-41. doi:

Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase - Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase

List K, Currie B, Scharschmidt TC, Szabo R, Shireman J, Molinolo A, Cravatt BF, Segre J, Bugge TH. J Biol Chem. 2007 Dec 14;282(50):36714-23. Epub 2007 Oct 16.