| Name | Recombinant Human INSL5/INSL7 Hybrid |
|---|---|
| Supplier | BioGems |
| Catalog | 130-05 |
| Category | Protein |
| Prices | $80.00, $195.00, $600.00, $1,800.00, $3,000.00 |
| Sizes | 5 µg, 25 µg, 100 µg, 500 µg, 1 mg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | E. Coli |
| Purity | Above 98% as determined by SDS-PAGE Analysis. |
| Bioactivity | Data not available. |
| Gene | INSL5 |
| Sequence | A-chai n: QDL QTLCCTDGC SMTDLSALC B- chain: RAAPYGVR LCGREFIRA VIFTCGGSR W |
| Description | The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide bonds. INSL7-INSL5 hybrid contains the B-chain of INSL7 (Relaxin-3), linked to the A-chain of INSL5. The INSL7-INSL5 hybrid protein can specifically activate the G protein coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant INSL7-INSL5 hybrid is a hetero-dimeric 5.2 kDa protein consisting of a 27 amino acid B-chain disulfide linked to a 21 amino acid A-chain. |
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