RABGEF1 Recombinant Protein (OPCA02524)

• Supplier: Aviva Systems Biology
• Catalog: OPCA02524
• Category: Protein
• Prices: $250.00
• Sizes: 50 µg
• Nature: Recombinant
• Source: Human
• Tag/Conjugation: His-SUMO-tag
• Purity: Greater than 90% as determined by SDS-PAGE.
• SwissProt/Accession: Q9UJ41
• Gene: RABGEF1
• Sequence: MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCV
• Description: RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010]